1. Observe the effects of DBS on anxiety, depression, and other mental disorders in patients with Parkinson's disease and other motor disorders before and after treatment, and preliminarily explore its mechanism of action from aspects such as immunology, endocrine, and brain network. 2. Apply DBS to the treatment of mental disorders such as obsessive-compulsive disorder, depression, schizophrenia, etc., and find ideal stimulation targets and implantation opportunities to obtain feasible clinical use plans, And explore the mechanism. 3. Expand the treatment scope of DBS and provide theoretical basis for neuroregulatory treatment of mental disorders. 4. Provide new ideas for the treatment of refractory mental disorders. 5. Cultivate professional and technical personnel for relevant basic and clinical research, and cultivate 3-5 graduate students to publish 2-3 related professional papers. Deep brain stimulation (DBS) is a new method of precise localization through stereotactic localization, in which stimulation electrodes are implanted at specific targets in the brain to achieve therapeutic goals. DBS has become the main treatment method for motor disorders. While treating the motor symptoms of these diseases, DBS also has a good relieving effect on the combined psychological symptoms such as anxiety and depression. In recent years, DBS has also achieved many exciting results in the surgical treatment of mental disorders, but the specific mechanism of action is still unclear. Therefore, this study aims to observe the impact of DBS on anxiety, depression, and other mental disorders in patients with Parkinson's disease and other motor disorders before and after treatment, explore its impact mechanism, and on this basis, preliminarily explore the feasibility of DBS treatment for refractory mental disorders such as obsessive-compulsive disorder, depression, schizophrenia, and explore specific implementation plans and mechanisms.