This position requires a strong industry background with at least 10-15 years of experience. The ideal candidate is proficient in operating a pharmaceutical pilot plant or a commercial facility in the downstream processing field. Professional knowledge and specific experience in modeling the application of oxygen mass transfer, unit volume power, carbon dioxide stripping model, container mixing characteristics, vortex size application, fluid dynamic shear, etc. in bioreactors. Candidates should have a strong background in cell metabolism, various mammalian cell lines, and a scientific mind. In addition, candidates should have knowledge and experience in designing bioreactor containers, and have a corresponding understanding of how key design attributes affect process performance. Hands-on experience in using various sizes of bioreactors (disposable bioreactors (SUBs) and traditional SS tanks) is required, and prior to application on these scales

The candidate will lead a team of 20-50 people in the field of clinical commercial downstream processing. The personnel will analyze historical data to support process amplification between clinical and commercial production facilities. This will include troubleshooting observed process differences, as well as deriving and improving current scaling techniques and tools. This position will also require characterization of blood vessels (containers), pilot commercial scale hands-on cell culture and fermentation, as well as related experimental plans, coordination, and report writing. Candidates need to have experience leading a team, a goal oriented mindset, and a capable attitude. Candidates will work with quality assurance, quality control, engineering, supply chain, PD, planning, regulation, logistics, project management and procurement.